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1.

Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer.

Lin, Jia-Ren; Wang, Shu; Coy, Shannon; Chen, Yu-An; Yapp, Clarence; Tyler, Madison; Nariya, Maulik K; Heiser, Cody N; Lau, Ken S; Santagata, Sandro; Sorger, Peter K.

Cell; 186(2): 363-381.e19, 2023 01 19.

Artículo en Inglés | MEDLINE | ID: mdl-36669472

2.

Spatially confined sub-tumor microenvironments in pancreatic cancer.

Grünwald, Barbara T; Devisme, Antoine; Andrieux, Geoffroy; Vyas, Foram; Aliar, Kazeera; McCloskey, Curtis W; Macklin, Andrew; Jang, Gun Ho; Denroche, Robert; Romero, Joan Miguel; Bavi, Prashant; Bronsert, Peter; Notta, Faiyaz; O'Kane, Grainne; Wilson, Julie; Knox, Jennifer; Tamblyn, Laura; Udaskin, Molly; Radulovich, Nikolina; Fischer, Sandra E; Boerries, Melanie; Gallinger, Steven; Kislinger, Thomas; Khokha, Rama.

Cell; 184(22): 5577-5592.e18, 2021 10 28.

Artículo en Inglés | MEDLINE | ID: mdl-34644529

3.

A modular master regulator landscape controls cancer transcriptional identity.

Paull, Evan O; Aytes, Alvaro; Jones, Sunny J; Subramaniam, Prem S; Giorgi, Federico M; Douglass, Eugene F; Tagore, Somnath; Chu, Brennan; Vasciaveo, Alessandro; Zheng, Siyuan; Verhaak, Roel; Abate-Shen, Cory; Alvarez, Mariano J; Califano, Andrea.

Cell; 184(2): 334-351.e20, 2021 01 21.

Artículo en Inglés | MEDLINE | ID: mdl-33434495

4.

Proteogenomic characterization of pancreatic ductal adenocarcinoma.

Cao, Liwei; Huang, Chen; Cui Zhou, Daniel; Hu, Yingwei; Lih, T Mamie; Savage, Sara R; Krug, Karsten; Clark, David J; Schnaubelt, Michael; Chen, Lijun; da Veiga Leprevost, Felipe; Eguez, Rodrigo Vargas; Yang, Weiming; Pan, Jianbo; Wen, Bo; Dou, Yongchao; Jiang, Wen; Liao, Yuxing; Shi, Zhiao; Terekhanova, Nadezhda V; Cao, Song; Lu, Rita Jui-Hsien; Li, Yize; Liu, Ruiyang; Zhu, Houxiang; Ronning, Peter; Wu, Yige; Wyczalkowski, Matthew A; Easwaran, Hariharan; Danilova, Ludmila; Mer, Arvind Singh; Yoo, Seungyeul; Wang, Joshua M; Liu, Wenke; Haibe-Kains, Benjamin; Thiagarajan, Mathangi; Jewell, Scott D; Hostetter, Galen; Newton, Chelsea J; Li, Qing Kay; Roehrl, Michael H; Fenyö, David; Wang, Pei; Nesvizhskii, Alexey I; Mani, D R; Omenn, Gilbert S; Boja, Emily S; Mesri, Mehdi; Robles, Ana I; Rodriguez, Henry.

Cell; 184(19): 5031-5052.e26, 2021 09 16.

Artículo en Inglés | MEDLINE | ID: mdl-34534465

5.

Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses.

Cui, Can; Wang, Jiawei; Fagerberg, Eric; Chen, Ping-Min; Connolly, Kelli A; Damo, Martina; Cheung, Julie F; Mao, Tianyang; Askari, Adnan S; Chen, Shuting; Fitzgerald, Brittany; Foster, Gena G; Eisenbarth, Stephanie C; Zhao, Hongyu; Craft, Joseph; Joshi, Nikhil S.

Cell; 184(25): 6101-6118.e13, 2021 12 09.

Artículo en Inglés | MEDLINE | ID: mdl-34852236

6.

Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.

Koikawa, Kazuhiro; Kibe, Shin; Suizu, Futoshi; Sekino, Nobufumi; Kim, Nami; Manz, Theresa D; Pinch, Benika J; Akshinthala, Dipikaa; Verma, Ana; Gaglia, Giorgio; Nezu, Yutaka; Ke, Shizhong; Qiu, Chenxi; Ohuchida, Kenoki; Oda, Yoshinao; Lee, Tae Ho; Wegiel, Babara; Clohessy, John G; London, Nir; Santagata, Sandro; Wulf, Gerburg M; Hidalgo, Manuel; Muthuswamy, Senthil K; Nakamura, Masafumi; Gray, Nathanael S; Zhou, Xiao Zhen; Lu, Kun Ping.

Cell; 184(18): 4753-4771.e27, 2021 09 02.

Artículo en Inglés | MEDLINE | ID: mdl-34388391

7.

Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer.

Banh, Robert S; Biancur, Douglas E; Yamamoto, Keisuke; Sohn, Albert S W; Walters, Beth; Kuljanin, Miljan; Gikandi, Ajami; Wang, Huamin; Mancias, Joseph D; Schneider, Robert J; Pacold, Michael E; Kimmelman, Alec C.

Cell; 183(5): 1202-1218.e25, 2020 11 25.

Artículo en Inglés | MEDLINE | ID: mdl-33142117

8.

Hear Pancreatic Cancer Stem Cells ROR.

Yao, Wantong; Maitra, Anirban.

Cell; 177(3): 516-518, 2019 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-31002791

9.

A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.

Lytle, Nikki K; Ferguson, L Paige; Rajbhandari, Nirakar; Gilroy, Kathryn; Fox, Raymond G; Deshpande, Anagha; Schürch, Christian M; Hamilton, Michael; Robertson, Neil; Lin, Wei; Noel, Pawan; Wartenberg, Martin; Zlobec, Inti; Eichmann, Micha; Galván, José A; Karamitopoulou, Eva; Gilderman, Tami; Esparza, Lourdes Adriana; Shima, Yutaka; Spahn, Philipp; French, Randall; Lewis, Nathan E; Fisch, Kathleen M; Sasik, Roman; Rosenthal, Sara Brin; Kritzik, Marcie; Von Hoff, Daniel; Han, Haiyong; Ideker, Trey; Deshpande, Aniruddha J; Lowy, Andrew M; Adams, Peter D; Reya, Tannishtha.

Cell; 177(3): 572-586.e22, 2019 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-30955884

10.

Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis.

Nanki, Kosaku; Toshimitsu, Kohta; Takano, Ai; Fujii, Masayuki; Shimokawa, Mariko; Ohta, Yuki; Matano, Mami; Seino, Takashi; Nishikori, Shingo; Ishikawa, Keiko; Kawasaki, Kenta; Togasaki, Kazuhiro; Takahashi, Sirirat; Sukawa, Yasutaka; Ishida, Hiroki; Sugimoto, Shinya; Kawakubo, Hirofumi; Kim, Jihoon; Kitagawa, Yuko; Sekine, Shigeki; Koo, Bon-Kyoung; Kanai, Takanori; Sato, Toshiro.

Cell; 174(4): 856-869.e17, 2018 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-30096312

11.

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.

Gee, Marvin H; Han, Arnold; Lofgren, Shane M; Beausang, John F; Mendoza, Juan L; Birnbaum, Michael E; Bethune, Michael T; Fischer, Suzanne; Yang, Xinbo; Gomez-Eerland, Raquel; Bingham, David B; Sibener, Leah V; Fernandes, Ricardo A; Velasco, Andrew; Baltimore, David; Schumacher, Ton N; Khatri, Purvesh; Quake, Stephen R; Davis, Mark M; Garcia, K Christopher.

Cell; 172(3): 549-563.e16, 2018 01 25.

Artículo en Inglés | MEDLINE | ID: mdl-29275860

12.

Conceptual and Experimental Tools to Understand Spatial Effects and Transport Phenomena in Nonlinear Biochemical Networks Illustrated with Patchy Switching.

Pompano, Rebecca R; Chiang, Andrew H; Kastrup, Christian J; Ismagilov, Rustem F.

Annu Rev Biochem; 86: 333-356, 2017 06 20.

Artículo en Inglés | MEDLINE | ID: mdl-28654324

13.

A gut response: Modulating chemotherapy efficacy with microbial metabolites.

Bauer, Kylynda C; Greten, Tim F.

Immunity; 56(4): 750-752, 2023 04 11.

Artículo en Inglés | MEDLINE | ID: mdl-37044066

14.

Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses.

Lavin, Yonit; Kobayashi, Soma; Leader, Andrew; Amir, El-Ad David; Elefant, Naama; Bigenwald, Camille; Remark, Romain; Sweeney, Robert; Becker, Christian D; Levine, Jacob H; Meinhof, Klaus; Chow, Andrew; Kim-Shulze, Seunghee; Wolf, Andrea; Medaglia, Chiara; Li, Hanjie; Rytlewski, Julie A; Emerson, Ryan O; Solovyov, Alexander; Greenbaum, Benjamin D; Sanders, Catherine; Vignali, Marissa; Beasley, Mary Beth; Flores, Raja; Gnjatic, Sacha; Pe'er, Dana; Rahman, Adeeb; Amit, Ido; Merad, Miriam.

Cell; 169(4): 750-765.e17, 2017 05 04.

Artículo en Inglés | MEDLINE | ID: mdl-28475900

15.

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis.

Roe, Jae-Seok; Hwang, Chang-Il; Somerville, Tim D D; Milazzo, Joseph P; Lee, Eun Jung; Da Silva, Brandon; Maiorino, Laura; Tiriac, Hervé; Young, C Megan; Miyabayashi, Koji; Filippini, Dea; Creighton, Brianna; Burkhart, Richard A; Buscaglia, Jonathan M; Kim, Edward J; Grem, Jean L; Lazenby, Audrey J; Grunkemeyer, James A; Hollingsworth, Michael A; Grandgenett, Paul M; Egeblad, Mikala; Park, Youngkyu; Tuveson, David A; Vakoc, Christopher R.

Cell; 170(5): 875-888.e20, 2017 Aug 24.

Artículo en Inglés | MEDLINE | ID: mdl-28757253

16.

Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.

Kortlever, Roderik M; Sodir, Nicole M; Wilson, Catherine H; Burkhart, Deborah L; Pellegrinet, Luca; Brown Swigart, Lamorna; Littlewood, Trevor D; Evan, Gerard I.

Cell; 171(6): 1301-1315.e14, 2017 Nov 30.

Artículo en Inglés | MEDLINE | ID: mdl-29195074

17.

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.

Ghoneim, Hazem E; Fan, Yiping; Moustaki, Ardiana; Abdelsamed, Hossam A; Dash, Pradyot; Dogra, Pranay; Carter, Robert; Awad, Walid; Neale, Geoff; Thomas, Paul G; Youngblood, Ben.

Cell; 170(1): 142-157.e19, 2017 Jun 29.

Artículo en Inglés | MEDLINE | ID: mdl-28648661

18.

PTPN2 regulates the generation of exhausted CD8⁺ T cell subpopulations and restrains tumor immunity.

LaFleur, Martin W; Nguyen, Thao H; Coxe, Matthew A; Miller, Brian C; Yates, Kathleen B; Gillis, Jacob E; Sen, Debattama R; Gaudiano, Emily F; Al Abosy, Rose; Freeman, Gordon J; Haining, W Nicholas; Sharpe, Arlene H.

Nat Immunol; 20(10): 1335-1347, 2019 10.

Artículo en Inglés | MEDLINE | ID: mdl-31527834

19.

TGF-ß Tumor Suppression through a Lethal EMT.

David, Charles J; Huang, Yun-Han; Chen, Mo; Su, Jie; Zou, Yilong; Bardeesy, Nabeel; Iacobuzio-Donahue, Christine A; Massagué, Joan.

Cell; 164(5): 1015-30, 2016 Feb 25.

Artículo en Inglés | MEDLINE | ID: mdl-26898331

20.

Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules.

Grabocka, Elda; Bar-Sagi, Dafna.

Cell; 167(7): 1803-1813.e12, 2016 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-27984728

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